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Anti-ITA2B Polyclonal Antibody
產品簡介:

Anti-ITA2B Polyclonal Antibody
應用 WB
稀釋比例WB 1:3000.
交叉反應Human

產品型號:fk2985Y

更新時間:2022-08-15

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產品介紹

Anti-ITA2B Polyclonal Antibody

英文名稱Anti-ITA2B Polyclonal Antibody
宿主Rabbit
別名ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
應用WB
稀釋比例WB 1:3000.
交叉反應Human
蛋白分子量113kDa
Gene ID3174
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human ITA2B
性狀液體
Public Immunogen Range

A synthetic peptide of human ITA2B

Subcellular LocationsCytoplasm Cell membrane
Swiss ProtP08514
克隆類型Polyclonal Antibody
背景資料Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Anti-ITA2B Polyclonal Antibody

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