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產(chǎn)品中心抗體Polyclonal AntibodyK106613PAnti-LIFR Polyclonal Antibody
產(chǎn)品型號：K106613P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：996
010-50973130
產(chǎn)品分類
| 英文名稱 | Anti-LIFR Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | CD118;LIF-R;SJS2;STWS;SWS |
| 應用 | WB |
| 稀釋比例 | WB 1:500-2000. |
| 交叉反應 | Human |
| 蛋白分子量 | 115kDa |
| Gene ID | 3977 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human LIFR |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human LIFR |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P42702 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
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