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Anti-Thioredoxin Polyclonal Antibody
產(chǎn)品簡介:

Anti-Thioredoxin Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng)Human

產(chǎn)品型號:K106714P

更新時間:2022-08-15

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產(chǎn)品介紹

Anti-Thioredoxin Polyclonal Antibody

英文名稱Anti-Thioredoxin Polyclonal Antibody
宿主Rabbit
別名TRDX;TRX;TRX1;TXN
應(yīng)用IHC
稀釋比例IHC 1:25-100.
交叉反應(yīng)Human
蛋白分子量12kDa
Gene ID7295
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human Thioredoxin
性狀液體
Public Immunogen RangeA synthetic peptide of human Thioredoxin
Subcellular LocationsNucleus Cytoplasm Secreted
Swiss ProtP10599
克隆類型Polyclonal Antibody
背景資料Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

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